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Hepatology in Children

The Role of Hepatology in Children

In the field of medicine, paediatric gastroenterologists and hepatologists play a vital role in providing specialised care to young patients. The significance of paediatric hepatology has been growing steadily, emphasising the need for expert healthcare professionals who can address the unique liver-related challenges faced by children. In this blog, we'll shed light on the field of paediatric GI and hepatology, the role of paediatric hepatologists, and the importance of children's hepatology in providing comprehensive care to young patients.

What Is Paediatric GI and Hepatology?

Paediatric gastroenterology is a medical speciality that focuses on treating gastrointestinal disorders in children with a primary focus on diagnosis, treatment, and management. With time, this field has expanded to include Paediatric hepatology, a subspecialty that specialises in treating children with liver disorders. Due to the increasing frequency of childhood lіvеr diseases, paediatric hepatology has emerged as a crucial subspecialty of paediatric medicine.

Paediatric GI and hepatology cover a wide range of illnesses, such as:

  • Metabolic liver diseases

  • Cirrhosis of the liver

  • Inflammatory bowel disease

  • Celiac disease

By specialising in this field, healthcare providers can ensure accurate diagnosis, timely intervention, and appropriate management of liver-related conditions in children.

Who Is a Paediatric Hepatologist?

Paediatric hepatologists are medical professionals who possess specialised training and expertise in diagnosing and treating liver diseases in children. They play a crucial role in providing comprehensive care to young patients by combining their knowledge of paediatric medicine with an in-depth understanding of hepatology.

A group of experts from various fields, including paediatric surgeons, radiologists, and nutritionists, work closely with Paediatric hepatologists. Together, they design individualised treatment programs that address the particular requirements of each patient. Their expertise lies in:

  • Interpreting liver function tests

  • Performing liver biopsies

  • Prescribing appropriate medications

  • Monitoring the progression of liver diseases

Along with helping children and their families through the challenges brought on by liver diseases, these experts also provide support and advice.

The Unique Challenges of Paediatric Hepatology

Paediatric hepatology presents unique challenges that distinguish it from hepatology in adult patients. The presentation and manifestations of liver diseases in children can be significantly different, making accurate diagnosis and monitoring essential. Paediatric hepatologists must consider the child's growth and development while designing treatment plans, as liver diseases can hurt the child’s growth.

Additionally, children's hepatology necessitates emotional and psychological support for young patients and their families. Dealing with liver disease can be overwhelming for children and their parents, and paediatric hepatologists play a crucial role in providing reassurance, addressing concerns, and promoting overall well-being.

Common Liver Conditions in Paediatric Hepatology

Several liver conditions are prevalent in paediatric hepatology, requiring specialised care and management. Some of the common conditions include:

  1. Biliary Atresia: Biliary atresia is the leading cause of liver transplantation in infants. It is a condition characterised by the obstruction or absence of the bile ducts, leading to liver damage and eventual failure. Early diagnosis and timely surgical intervention are crucial for improved outcomes.

  2. Hepatitis B and C in children: While primarily considered as diseases affecting adults, hepatitis B and C can also affect children through various modes of transmission. Paediatric hepatologists play a vital role in managing and treating hepatitis B and C in young patients, focusing on antiviral therapy, monitoring, and prevention strategies.

  3. Alagille Syndrome: Alagille Syndrome is a genetic disorder that affects multiple organs, including the liver. It is characterised by bile duct abnormalities, leading to cholestasis and liver dysfunction. Paediatric hepatologists collaborate with other specialists to manage the complex manifestations of Alagille Syndrome.

  4. Wilson's Disease: Wilson's Disease is an inherited disorder of copper metabolism, resulting in its accumulation in various organs, including the liver. Paediatric hepatologists diagnose and manage this condition through long-term treatment plans to prevent liver damage and associated complications.

Multidisciplinary Approach to Paediatric Hepatology

The field of paediatric hepatology emphasises the value of a thorough and multidisciplinary approach to ensure the best possible care because іt іs aware of the complexity of liver diseases in children. Collaboration with various healthcare professionals is vital to address the diverse aspects of liver diseases and ensure the well-being of young patients. Here are the key components of the multidisciplinary approach in paediatric hepatology:

1. Paediatric Surgeons

Paediatric hepatologists work closely with paediatric surgeons, particularly in cases where surgical intervention is required. For conditions such as biliary atresia or liver transplantation, a collaborative effort between paediatric hepatologists and paediatric surgeons is crucial. Together, they determine the appropriate surgical procedures, timing, and post-operative management, aiming to improve outcomes and long-term prognosis.

2. Radiologists

Radiologists specialising in paediatric imaging play a vital role in diagnosing and monitoring liver diseases. They utilise various imaging modalities such as ultrasound, computed tomography (CT), magnetic resonance imaging (MRI), and hepatobiliary scintigraphy to assess liver structure, detect abnormalities, and guide interventions. Paediatric hepatologists closely collaborate with radiologists to interpret imaging findings and develop treatment plans based on the diagnostic information provided.

3. Nutritionists

Optimal nutrition plays a crucial role in the management of liver diseases in children. Nutritionists specialising in paediatric gastroenterology and hepatology work closely with paediatric hepatologists to develop tailored nutritional plans. They assess the nutritional status of young patients, provide dietary guidance, and monitor nutritional support, ensuring that the specific nutritional needs of children with liver diseases are met. 

Final Words

Paediatric hepatology plays a pivotal role in providing specialised care for children with liver diseases. The unique challenges posed by liver conditions in young patients require the expertise of paediatric hepatologists, who combine their knowledge of paediatric medicine with a deep understanding of hepatology. 

If you are afraid that your child may be at risk of liver disorders, consult an expert hepatologist at a super-specialty hospital immediately!

FAQs

1. Why is specialised hepatology care important for children?


Children’s livers differ significantly from adults, and specialised care ensures accurate diagnosis and age-appropriate treatments tailored to their developing bodies.

2. What are some common liver diseases in children?


Common liver conditions include biliary atresia, hepatitis, fatty liver disease, and metabolic liver disorders like Wilson’s disease.

3. How are liver diseases in children diagnosed?


Diagnosis typically involves blood tests, imaging studies like ultrasounds or MRIs, and sometimes liver biopsies to assess the extent and nature of the disease.

4. What symptoms might indicate a liver problem in a child?


Symptoms include yellowing of the skin or eyes (jaundice), persistent vomiting, abdominal pain, swelling, dark urine, or pale stools.

5. Can children recover fully from liver diseases?


Many paediatric liver conditions are treatable, especially when diagnosed early. Recovery depends on the condition's severity and response to treatment.

Citations

Chilot, D., Belay, D. G., Shitu, K., Mulat, B., Alem, A. Z., & Geberu, D. M. (2022). Prevalence and associated factors of common childhood illnesses in sub-Saharan Africa from 2010 to 2020: a cross-sectional study. BMJ Open, 12(11), e065257. https://doi.org/10.1136/bmjopen-2022-065257

Yoeli, D., Choudhury, R. A., Sundaram, S. S., Mack, C. L., Roach, J. P., Karrer, F. M., Wachs, M. E., & Adams, M. A. (2022). Primary vs. salvage liver transplantation for biliary atresia: A retrospective cohort study. Journal of Pediatric Surgery, 57(10), 407–413. https://doi.org/10.1016/j.jpedsurg.2021.12.027

Członkowska, A., Litwin, T., Dusek, P., Ferenci, P., Lutsenko, S., Medici, V., Rybakowski, J. K., Weiss, K. H., & Schilsky, M. L. (2018). Wilson disease. Nature Reviews Disease Primers, 4(1). https://doi.org/10.1038/s41572-018-0018-3

Diaz-Frias, J., & Kondamudi, N. P. (2023, August 12). Alagille syndrome. StatPearls - NCBI Bookshelf. https://www.ncbi.nlm.nih.gov/books/NBK507827/

Kelly, D. (2006). Viral hepatitis B and C in children. Journal of the Royal Society of Medicine, 99(7), 353–357. https://doi.org/10.1258/jrsm.99.7.353

Dr. Neelam Mohan
Liver Transplant
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