Intraepidermal squamous cell carcinoma or Bowen’s disease is named after the American dermatologist John. T. Bowen. Bowen’s disease is a skin disease that marks the early onset of skin cancer. The mai..
Intraepidermal squamous cell carcinoma or Bowen’s disease is named after the American dermatologist John. T. Bowen. Bowen’s disease is a skin disease that marks the early onset of skin cancer. The main symptom of Bowen’s disease is a red, scaly patch.The disease affects the squamous cells in the outermost skin layer. It starts as a slow growing small patch on sun-exposed area like hands, neck, face, etc. The formation of a boil or bump on the affected area indicates formation of aggressive squamous cell cancer. If left untreated, it can spread further, affecting a larger area. The patch grows at a very slow rate and may bleed at times. It may be mistaken with a ringworm or psoriasis disease. Patches in this disease can be a few millimeters in diameter, but can grow to centimeters.
The first symptom of Bowen’s disease is a red looking patch with an uneven boundary. The patch may appear on an area of the skin, especially the sun exposed area. Few of the other symptoms include:
- Ulcer.
- Bleeding lump.
The main causes of this disease include:
- Exposure to UV radiations.
- Formation of mutant clone gene, p53.
- Uncontrolled growth of skin cells.
The major risk factors of this disease include:
- Long-term sun exposure and sun burns.
- Previous history of carcinoma.
- Skin injury that caused skin damage or scarring.
- Skin inflammation like eczema.
- Human papillomavirus (HPV) that affects the skin lining and mucosa.
In order to prevent the occurrence of this disease, one should take care of the following:
- Using a sunscreen which has at least SPF 15.
- Staying in the shade as much as possible.
- Covering up the skin while exposure to sun.
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Our superspecialist doctors provide the highest quality of care through a team-based, doctor-led model. Trained at some of the world's most renowned i..... Continue Reading