Bone Marrow Transplant
Rapid and uncontrollable production of abnormal white blood cells known as blasts causes leukaemia and can be either acute (growing quickly) or chronic (growing slowly). White blood cells, including lymphocytes and neutrophils, normally fight against infection. The vast number of abnormal white blood cells makes them unable to fight infection and also interferes with the proper production and functioning of the blood cells.
Thalassemia is an inherited blood disorder passed down through genes. It affects the body's ability to produce haemoglobin, a protein in red blood cells that carries oxygen throughout the body. There are two main types: alpha and beta-thalassemia. The severity of symptoms varies depending on the type and number of gene mutations inherited. Some people may experience mild or no symptoms, while others may have severe anaemia that leads to fatigue, weakness, and shortness of breath. Thalassemia can be managed with regular blood transfusions and chelation therapy to remove excess iron build-up from frequent transfusions.
A blood cancer that affects the lymphocytes or the lymphatic system of the body, including lymph nodes, is called lymphoma. Lymphocytes are white blood cells that fight infections in the body. These lymphoma cells then endanger the immune system. Lymphoma is the most common type of blood cancer in adults, and more than half the cases diagnosed are attributed to this type
Sickle cell anaemia is the most common form of sickle cell disease (SCD). It is a group of inherited blood disorders affecting red blood cells. Haemoglobin, the protein in red blood cells responsible for oxygen transport, is abnormal in SCD. This abnormality causes red blood cells to become sickle-shaped, stiff, and sticky. These sickle cells die prematurely, leading to a constant shortage of healthy red blood cells. Additionally, their shape can obstruct blood flow in small blood vessels, causing severe pain and complications like infections, acute chest syndrome, and stroke.